Baerlocher, G.M., Mak, J., Tien, P., and Lansdorp, P.M. (2002). Telomere length measurement by fluorescence in situ hybridization and flow cytometry: Tips and pitfalls. Cytometry 47, 89-99.

Ben Yehuda, A., Globerson, A., Krichevsky, S., Bar On, H., Kidron, M. et al. (2000). Ageing and the mismatch repair system. Mech. Ageing Dev. 121, 173-179.

Collins, A.R., Duthie, S.J., and Dobson, V.L. (1993). Direct enzymatic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 14, 1733-1735.

Dempsey, J.L., Morley, A.A., Seshadri, R.S., Emmerson, B.T., Gordon, R., and Bhagat, C.I. (1983). Detection of the carrier state for an X-linked disorder, the Lesch-Nyhan syndrome, by the use of lymphocyte cloning. Hum. Genet. 64, 288-290.

Franceschi, C., Monti, D., Sansoni, P., and Cossatizza, A. (1995). The immunology of exceptional individuals: the lesson of centenarians. Immunol. Today 16, 12-16.

Granger, M.P., Wright, W.E., and Shay, J.W. (2002). Telomerase in cancer and aging. Crit. Rev. Oncol. Hematol. 41, 29-40.

Hyland, P., Barnett, C., Pawelec, G., and Barnett, Y. (2001). Age-related accumulation of oxidative DNA damage and alterations in levels of p16INK4a/CDKN2a, p21WAFi/CIPi/SDI1 and p27KIP1 in human CD4+ T cell clones in vitro. Mech. Ageing Dev. 122, 1151-1167.

Kim, S.H., Kaminker, P., and Campisi, J. (2002). Telomeres, aging and cancer: In search of a happy ending. Oncogene 21, 503-511.

King, C.M., Bristow-Craig, H.E., Gillespie, E.S., and Barnett, Y.A. (1997). In vivo antioxidant status, DNA damage, mutation and DNA repair capacity in cultured lymphocytes from healthy 75-80 year old humans. Mut. Res. 377, 137-147.

Krichevsky, S., Pawelec, G., Gural, A., Effros, R.B., Globerson, A., Ben Yehuda D. et al. (2004). Age related microsatellite instability in T cells from healthy individuals. Exp. Gerontol. 39, 507-515.

Larbi, A., Douziech, N., Dupuis, G., Khalil, A., Pelletier, H., Guerard, K.P. et al. (2004a). Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes. J. Leuk. Biol. 75, 373-381.

Larbi, A., Douziech, N., Khalil, A., Dupuis, G., Gherairi, S., Guerard, K.P. et al. (2004b). Effects of methyl-beta-cyclodextrin on T lymphocytes lipid rafts with aging. Exp. Gerontol. 39, 551-558.

Loeb, L.A. (1994). Microsatellite instability: Marker of a mutator phenotype in cancer. Cancer Res. 54, 5059-5063.

Lombard, D.B., Chua, K.F., Mostoslavsky, R., Franco, S., Gostissa, M., and Alt, F.W. (2005). DNA repair, genome stability and ageing. Cell 120, 497-512.

Maini, M.K., Soares, M.V., Zilch, C.F., Akbar, A.N., and Beverley, P.C. (1999). Virus-induced CD8+ T cell clonal expansion is associated with telomerase up-regulation and telomere length preservation: A mechanism for rescue from replicative senescence. J. Immunol. 162, 4521-4526.

McCarron, M., Osborne, Y., Story, C., Dempsey, J.L., Turner, R., and Morley, A. (1987). Effect of age on lymphocyte proliferation. Mech. Ageing Dev. 41, 211-218.

Neri, S., Cattini, L., Facchini, A., Pawelec, G., and Mariani, E. (2004). Microsatellite instability in in vitro ageing of T lymphocyte clones. Exp. Gerontol. 39, 499-505.

Neri, S., Gardini, A., Facchini, A., Olivieri, F., Franceschi, C., Ravaglia, G. et al. (2005). Mismatch Repair System and aging: Microsatellite instability in peripheral blood cells from differently aged participants. J. Gerontol. 60A, 285-292.

Pawelec, G., Müller, R., Rehbein, A., Hahnel, K., and Ziegler, B. (1998). Extrathymic T cell differentiation in vitro from human CD34+ stem cells. J. Leuk. Biol. 64, 733-739.

Pawelec, G., Fernandez, N., Brocker, T., Schneider, E.M., Festenstein, H., and Wernet, P. (1988). DY determinants, possibly associated with novel class II molecules, stimulate autoreactive CD4+ T cells with suppressive activity. J. Exp. Med. 167, 243-261.

Pawelec, G., Sansom, D., Rehbein, A., Adibzadeh, M., and Beckman, I. (1996). Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human CD4+ TCR2+ cultured T cell clones. Exp. Gerontol. 31, 655-668.

Pawelec, G., Rehbein, A., Haehnel, K., Merl, A., and Adibzadeh, M. (1997). Human T cell clones in long-term culture as a model of immunosenescence. Immunol. Rev. 160, 31-42.

Pawelec, G., Barnett, Y., Mariani, E., and Solana, R. (2002). Human CD4+ T cell clone longevity in tissue culture: lack of influence of donor age or cell origin. Exp. Gerontol. 37, 265-269.

Pawelec, G., Akbar, A., Caruso, C., Effros, R., Grubeck-Loebenstein, B., and Wikby, A. (2004). Is immunosenescence infectious? Trends Immunol. 25, 406-410.

Podlutsky, A., Bastlova, T., and Lambert, B. (1996). Reduced proliferation rate of hypoxanthine-phosphoribosyl transfer-ase mutant human T-lymphocytes in vitro. Environ. Mol. Mutagen. 28, 13-18.

Rapi, S., Caldini, A., Fanelli, A., Berti, P., Lisi, E., Anichini, E. et al. (1996). Flow cytometric measurement of DNA content in human solid tumors: A comparison with cytogenetics. Cytometry 26, 192-197.

Rufer, N., Dragowska, W., Thornbury, G., Roosnek, E., and Lansdorp, P.M. (1998). Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat. Biotechnol. 16, 743-747.

Singh, N.P., McCoy, M.T., Tice, R.R., and Schneider, E.L. (1988). A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res. 175, 184-191.

Starostik, P., Greiner, A., Schwarz, S., Patzner, J., Schultz, A., and Muller-Hermelink, H.K. (2000). The role of microsatellite instability in gastric low- and high-grade lymphoma development. Am. J. Pathol. 157, 1129-1136.

Wikby, A., Ferguson, F., Forsey, R., Thompson, J., Strindhall, J., Lofgren, S. et al. (2005). An immune risk phenotype, cognitive impairment and survival in very late life: The impact of allostatic load in Swedish Octo- and Nonagenarian humans. J. Gerontol. B 60, 556-565.

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