Figure 42.4 Effect of pan-caspase inhibitors on infarct volume measured 48 hours after neonatal ischemia in P7 rat brain (neonatal stroke model). The drug was given five minutes before clip removal and consisted of a single intraperitoneal injection of either BAF in 10% DMSO (n = 16) or vehicle (10% DMSO, n = 15) (A) or Q-VD-OPH (B, see text). Control ischemic rats (n =14 and 16, respectively) also were studied. Data are mean ± SEM (bar). BAF did not induce a significant reduction of infarct volume (N.S., not significant) as compared to Q-VD-OPH (p = 0.04, Mann-Whitney test).


Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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