New World Monkeys

The New World monkeys share some similarities in reproductive aging with their Old World counterparts, such as decreased follicular numbers, reduced numbers of steroid receptors, and lower levels of estrogen and progesterone with higher LH levels in anovulatory females (Tardif et al., 1992). However, these animals do not undergo menstruation; rather, they have an estrous cycle (Hendrickx et al., 1995). Additionally, these animals appear to have moderate levels of estrogen and progesterone in the anovulatory phase of life (see Figure 43.3), as compared to the low levels seen in Old World monkeys, and exhibit a shorter life span.

Evidence of active luteal cell masses on the ovaries of these anovulatory females has been reported, distinguishing them from their Old World counterparts (Tardif et al., 1992) and suggests this as a possible source of these hormones. This difference in hormone levels probably relates to the ability of NWMs to maintain bone mass into the later stages of life, and may provide a unique mechanism for studying the role of estrogen in age-related diseases and disease resistance. Furthermore, their small size and tractability, combined with the absence of susceptibility to pathogens such as Herpes B, which are infectious to humans, make these an attractive model for biomedical studies (Abbott et al., 2003).

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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