How Can Place Cells Be Useful for the Study of Memory and Aging

CA1 and CA3 pyramidal cells reflect how spatial information is processed and stored in the hippocampus. Because place cells are not simply sensory neurons, because place cells are stable over time and repetition, because place cells clearly use the visual landmarks, and because place cells form new spatial representations of new environments, they provide an intriguing window into the formation of memories by the brain. Furthermore, consistent spatial representations are necessary for correct performance on spatial tasks and serve as a likely step in the mechanisms of spatial navigation and memory. Because these are precisely the behavioral impairments from which some aged individuals suffer, researchers have turned to place cells in order to tighten the connection between the behavioral deficits of aged animals and information processing capabilities within the hippocampus region. Hence, comparing the information processing of place cells of young and aged rats can yield unique insight into what goes wrong in the hippocampus of aged memory-impaired individuals.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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