Accumulating evidence indicates similar pathophysiologic mechanisms and risk factors underlying both osteoporosis and CVD, including age, sedentary lifestyle, dyslipidemia, hypertension, and diabetes, among others. Furthermore, therapeutic agents used for treatment of osteoporosis appear to have beneficial effects on atherosclerosis and vice versa. The prospect of newer therapeutic agents that could treat both osteoporosis and atherosclerosis simultaneously is an exciting possibility requiring further investigation.

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