Amyloid Hypothesis And A Amyloidosis

The characteristic pathological signature of AD noted by Alzheimer is the presence of deposits of A/ peptide in extracellular plaques accompanied by tau deposits in intracellular tangles. The weight of the genetic evidence from familial forms of AD supports the A/ peptide as a prime mover in the etiology of the disease (Hardy and Selkoe, 2002). While it is clear that mutations in /APP can cause AD in the genetic cases, sporadic AD must involve other factors. If it is true that multimeric A/ is either an initiating factor and/or a chronic stressor, strategies to alleviate these effects should alter the course of the disease.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook


Post a comment