Pseudomonas spp

Pseudomonas spp. may be isolated from the respiratory, digestive, and genital systems of rats and mice, the more common ones being P. aeruginosa and P. diminuta. P. aeruginosa causes conjunctivitis and rhinitis and, under more severe or experimental conditions, pneumonia and septicemia in rats and guinea pigs.5 In septicemic animals, abscessation of the liver, spleen, kidneys, and middle ears may be observed. Disease due to P. aeruginosa is mainly observed in immune-deficient, immune-suppressed, or stressed animals,87 and, in general, it is secondary to something else. The prevalences in infected colonies of immune-competent animals kept in a high quality environment seldom reach more than 5 to 10%, but the prevalence of diseased animals in colonies of immune-deficient animals kept under poor environmental conditions may reach 100%, e.g., during ventilation breakdowns. Poor hygienic conditions, especially in relation to water used for drinking and cleaning may play an important role in the spread of Pseudomonas spp. P. fluorescens and probably also some other Pseudomonas spp. produce mucous in drinking nipples, which, however, is not known to have any impact on the animals. This condition is normally prevented by acidification of the drinking water with hydrochloric or citric acid.

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