Transgenic mouse models are being used to investigate cigarette smoke-induced emphysema.31 The cigarette-smoking protocol consists of placing mice in a polypropylene whole-body inhalation chamber containing inlet pores and an exhaust pore. Smoke is generated through a 50-mL glass syringe equipped with a cigarette holder from one or multiple unfiltered cigarettes. The exposure period usually is long term on a daily basis. A typical protocol is exposure 6 days per week, for 6 months. Mice typically demonstrate progressive inflammatory cell recruitment beginning within the first month of smoking followed by airspace enlargement after 3 to 4 months of cigarette exposure.

Beating The Butt On Your Own

Beating The Butt On Your Own

Need To Stop Smoking? Are You Willing To Follow My Powerful Strategies To Stop Smoking And Vividly Transform Your Life Today? Proven Tips, Tools and Tactics To Stop Smoking And Live An Awesome Life You Always Wanted.

Get My Free Ebook

Post a comment