Bordetella bronchiseptica

Bordetella bronchiseptica may be isolated from rabbits and guinea pigs, occasionally from rats, and seldom from mice, hamsters, and gerbils.5 It may cause pneumonia, pleuritis, and pericarditis in guinea pigs, which might be fatal, especially if the animal carries other respiratory pathogens.5 In rabbits, disease is mainly subclinical and characterized by focal chronic interstitial pneumonia.41

Figure 11.3 Certain transgenic knock-out mouse strains suffer from gastric ulcers, colitis, and rectal prolapses, as shown by this gastric ulcer in a plasminogen knock-out mouse. (Photo courtesy Kirsten Dahl.)
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