Antibiotic Treatment

Antibiotics have been used for the total eradication of specific pathogenic bacteria in immune-competent animals. This method, known as selective decontamination, has been more or less successfully applied to mice,227 guinea pigs,228 rabbits,229 and dogs.230 Mice may even be made germ-free by decontamination.231 However, care should be taken, as the effect of the antibiotic treatment may simply be that the microorganism can no longer be detected, and not that it has been eliminated forever.232

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