Treatment Regimen

The recommended treatment regimen for latanoprost, travoprost, and bimatoprost is one drop applied topically once daily in the evening. Evening, rather than morning, administration appears to be more efficacious and may block the early morning diurnal spike in IOP that may be observed in many patients.29 With the exception of unoprostone, which has a recommended dosage of twice daily, none of the other PGs should be used more than once daily since more frequent dosage decreases the IOP-lowering effect.2,4,44

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