1. Kobelt-Nguyen G, Gerdtham UG, Alm A. Costs of treating primary open-angle glaucoma and ocular hypertension: a retrospective, observational two-year chart review of newly diagnosed patients in Sweden and the United States. J Glaucoma. 1998;7(2): 95-104.

2. Kass MA, et al. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120(6):701-713, 829-830.

3. Lavin MJ, et al. The influence of prior therapy on the success of trabeculectomy. Arch Ophthalmol. 1990;108(11):1543-1548.

4. Broadway DC, et al. Adverse effects of topical antiglaucoma medication. II. The outcome of filtration surgery. Arch Ophthalmol. 1994;112(11):1446-1454.

5. Chrai SS, et al. Drop size and initial dosing frequency problems of topically applied ophthalmic drugs. J Pharm Sci. 1974;63(3):333-338.

6. Kronfeld PC. The efficacy of combinations of ocular hypotensive drugs. A tonographic approach. Arch Ophthalmol. 1967;78(2):140-146.

7. Demailly P, Kerisel JB. [Combination of 2 percent pilocarpine—5 percent neosy-nephrine in the treatment of chronic and aphakic glaucoma]. Arch Ophthalmol Rev Gen Ophthalmol. 1967;27(7):683-696.

8. Krieglstein GK, Leydhecker W. [The pressure reducing effects of pilocarpin in combination with dipivalyl-epinephrine in glaucoma simplex]. Klin Monatsbl Augenheilkd. 1979;175(1):86-90.

9. Trotta N, O'Connor R. Efficacy of a combination solution of epinephrine and pilocarpine. Eye Ear Nose Throat Mon. 1971;50(9):350-352.

10. Knupp JA, et al. Combined timolol and epinephrine therapy for open angle glaucoma. Surv Ophthalmol. 1983;28(suppl):280-285.

11. Hovding G, Aasved H. Timolol/pilocarpine combination eye drops in open angle glaucoma and in ocular hypertension. A controlled randomized study. Acta Ophthalmol (Copenh). 1987;65(5):594-601.

12. Maclure GM, et al. Effect on the 24-hour diurnal curve of intraocular pressure of a fixed ratio combination of timolol 0.5% and pilocarpine 2% in patients with COAG not controlled on timolol 0.5%. Br J Ophthalmol. 1989;73(10):827-831.

13. Moriarty AP, Dowd TC, Trimble RB. Clinical experience with a fixed dose combination therapy of timolol and pilocarpine used twice daily in the management of chronic open angle glaucoma. Eye. 1994;8(pt 4):410-413.

14. Robin AL. Ocular hypotensive efficacy and safety of a combined formulation of be-taxolol and pilocarpine. Trans Am Ophthalmol Soc. 1996;94:89-103.

15. Clineschmidt CM, et al. A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group. Ophthalmology. 1998;105(10):1952-1959.

16. Boyle JE, et al. A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group. Ophthalmology. 1998;105(10):1945-1951.

17. Strohmaier K, et al. The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group. Ophthalmology. 1998;105(10):1936-1944.

18. Choudhri S, Wand M, Shields MB. A comparison of dorzolamide-timolol combination versus the concomitant drugs. Am J Ophthalmol. 2000;130(6):832-833.

Gugleta K, Orgul S, Flammer J. Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzo-lamide, in Swiss ophthalmologists' offices. Curr Med Res Opin. 2003;19(4):330-335.

Bacharach J, Delgado MF, Iwach AG. Comparison of the efficacy of the fixed-combination timolol/dorzolamide versus concomitant administration of timolol and dorzolamide. J Ocul Pharmacol Ther. 2003;19(2):93-96.

Honrubia FM, Larsson LI, Spiegel D. A comparison of the effects on intraocular pressure of latanoprost 0.005% and the fixed combination of dorzolamide 2% and timolol 0.5% in patients with open-angle glaucoma. Acta Ophthalmol Scand. 2002; 80(6):635-641.

Konstas AG, et al. Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination. Ophthalmology. 2003;110(7):1357-1360.

Orzalesi N, et al. Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension. Acta Ophthalmol Scand. 2002; 236(suppl):55.

Fechtner RD, et al. Efficacy of the dorzolamide/timolol fixed combination versus la-tanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies. J Ocul Pharmacol Ther. 2005;21(3):242-249.

Fechtner RD, et al. Efficacy and tolerability of the dorzolamide 2%/timolol 0.5% combination (Cosopt) versus 0.005% (Xalatan) in the treatment of ocular hypertension or glaucoma: results from two randomized clinical trials. Acta Ophthalmol Scand. 2004;82(1):42-48.

Day DG, et al. Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension. Am J Ophthalmol. 2003;135(2):138-143. Sall KN, et al. Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability. Ophthalmology. 2003;110(3):615-624.

Zabriskie N, Netland PA. Comparison of brimonidine/latanoprost and timolol/dor-zolamide: two randomized, double-masked, parallel clinical trials. Adv Ther. 2003; 20(2):92-100.

Alm A, et al. Latanoprost administered once daily caused a maintained reduction of intraocular pressure in glaucoma patients treated concomitantly with timolol. Br J Ophthalmol. 1995;79(1):12-16.

Rulo AH, Greve EL, Hoyng PF. Additive effect of latanoprost, a prostaglandin F2 alpha analogue, and timolol in patients with elevated intraocular pressure. Br J Ophthalmol. 1994;78(12):899-902.

Orengo-Nania S, et al. Evaluation of travoprost as adjunctive therapy in patients with uncontrolled intraocular pressure while using timolol 0.5%. Am J Ophthalmol. 2001; 132(6):860-868.

Higginbotham EJ, et al. Latanoprost and timolol combination therapy vs monotherapy: one-year randomized trial. Arch Ophthalmol. 2002;120(7):915-922. Pfeiffer N. A comparison of the fixed combination of latanoprost and timolol with its individual components. Graefes Arch Clin Exp Ophthalmol. 2002;240(11):893-899.

34. Bucci MG. Intraocular pressure-lowering effects of latanoprost monotherapy versus latanoprost or pilocarpine in combination with timolol: a randomized, observer-masked multicenter study in patients with open-angle glaucoma. Italian Latanoprost Study Group. J Glaucoma. 1999;8(1):24-30.

35. Konstas AG, et al. A comparison of once-daily morning vs evening dosing of concomitant latanoprost/timolol. Am J Ophthalmol. 2002;133(6):753-757.

36. Stewart WC, et al. Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily. Acta Ophthalmol Scand. 2003;81(3):242-246.

37. Konstas AG, et al. Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%. Eye. 2004;18(12):1264-1269.

38. Shin DH, Feldman RM, Sheu WP. Efficacy and safety of the fixed combinations la-tanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure. Ophthalmology. 2004;111(2):276-282.

39. Barnebey HS, et al. The safety and efficacy of travoprost 0.004%/timolol 0.5% fixed combination ophthalmic solution. Am J Ophthalmol. 2005;140(1):1-7.

40. Hughes BA, et al. A three-month, multicenter, double-masked study of the safety and efficacy of travoprost 0.004%/timolol 0.5% ophthalmic solution compared to travoprost 0.004% ophthalmic solution and timolol 0.5% dosed concomitantly in subjects with open angle glaucoma or ocular hypertension. J Glaucoma. 2005;14(5):392-399.

41. Schuman JS, et al. Efficacy and safety of a fixed combination of travoprost 0.004%/ timolol 0.5% ophthalmic solution once daily for open-angle glaucoma or ocular hypertension. Am J Ophthalmol. 2005;140(2):242-250.

42. Craven ER, et al. Brimonidine and timolol fixed-combination therapy versus mono-therapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension. J Ocul Pharmacol Ther. 2005;21(4):337-348.

43. Sherwood MB, et al. Twice-daily 0.2% brimonidine-0.5% timolol fixed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial. Arch Ophthalmol. 2006;124(9): 1230-1238.

44. Goni FJ. 12-Week study comparing the fixed combination of brimonidine and timolol with concomitant use of the individual components in patients with glaucoma and ocular hypertension. Eur J Ophthalmol. 2005;15(5):581-590.

45. Realini T, Fechtner RD. 56,000 ways to treat glaucoma. Ophthalmology. 2002; 109(11):1955-1956.

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