Prostaglandin Analogs

Thomas W. Hejkal and Carl B. Camras

2.1 Mechanism of Action, 34

2.2 Indications, 35

2.3 Contraindications, 36

2.4 Treatment Regimen, 36

2.5 Side Effects, 37

2.5.1 Conjunctival Hyperemia, 37

2.5.2 Iris Color Changes, 38

2.5.3 Eyelash Changes, 39

2.5.4 Uveitis, 39

2.5.5 Cystoid Macular Edema, 40

2.5.6 Other Local Side Effects, 41

2.5.7 No Systemic Side Effects, 41

2.6 Drug Interactions, 41

2.7 IOP Reduction in Clinical Trials, 42

2.8 Clinical Studies on Additivity, 43

2.8.1 Beta Blockers, 44

2.8.2 Carbonic Anhydrase Inhibitors, 44

2.8.3 Cholinergic Agonists, 44

2.8.4 Adrenergic Agonists, 45

2.8.4 Fixed Combinations With PG Analogs, 45

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