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Note: P < 0.05 when comparing compliance of once- and twice-daily groups with that of either three- or four-times-daily groups.

Source: Modified by permission of the publisher from Greenberg RN. Overview of patient compliance with medication dosing: a literature review. Clin Ther. 1984;6:591-599. Copyright 1984 by Excerpta Medica, Inc.

Note: P < 0.05 when comparing compliance of once- and twice-daily groups with that of either three- or four-times-daily groups.

Source: Modified by permission of the publisher from Greenberg RN. Overview of patient compliance with medication dosing: a literature review. Clin Ther. 1984;6:591-599. Copyright 1984 by Excerpta Medica, Inc.

medication), and are more likely to miss doses in the middle of the day for this

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