The indications for use for all OBBs as approved by the FDA are quite similar, although the language in the approved labeling differs. In general, OBBs are indicated for the treatment of elevated IOP in patients with ocular hypertension or open-angle glaucoma. The drugs may be used alone or in combination with other IOP-lowering medications. Specific information about each drug can be found in the package insert or in a reference such as the Physicians' Desk Reference for Ophthalmic Medications.

While the product labeling lists only ocular hypertension and open-angle glaucoma as indications for use, the OBBs have been accepted and can be effective for treatment of other causes of elevated IOP such as secondary glaucomas and angle closure.

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