Adrenergic Agents

Elliott M. Kanner and Howard I. Savage

4.1 Adrenergic Physiology in the Eye, 79

4.2 Pharmacology, 81

4.3 Nonselective Agonists, 81

4.3.1 Epinephrine, 81

4.3.2 Dipivefrin, 82

4.4 Alpha-Selective Agonists, 83

4.4.1 Clonidine, 83

4.4.2 Apraclonidine, 84

4.4.2.1 Pharmacology, 84

4.4.2.2 Mechanism of Action, 84

4.4.2.4 Indications, 88

4.4.3 Brimonidine, 92

4.4.3.1 Pharmacology, 92

4.4.3.2 Mechanism of Action, 92

4.4.3.3 Efficacy, 92

4.4.3.5 Indications, 94

4.4.3.6 Neuroprotection, 94

4.5 Conclusion, 95

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