Drug Delivery Systems

Ocusert Pilo System

Commonly used ophthalmic drug formulations, such as solutions, gels, suspensions, and ointments, deliver drugs at rates that follow first-order kinetics, in which the concentration of the drug transferred to the eye decreases exponentially with time. To achieve a constant concentration of the drug in the precorneal tear film and create a steady-state concentration in the tissues, an ophthalmic drug delivery system needs to be designed to deliver a specific drug at a zero-order kinetic rate. At...