Metronidazole is an antibiotic which has a specificity against pathogenic anaerobes (79). Metronidazole structurally is a 5-nitroimidazole. The compound has been shown to be mutagenic in the Ames assay. This activity is lost when tester strains deficient in nitroreductase are used in the assay. The nitro group is reduced to amine group prior to ring cleavage which yields acetamide and N-(2-hydroxyethyl) oxamic acid. Therefore the amine intermediate generated by bacterial action is not stable, and breaks down to simpler metabolites.

Pregnancy And Childbirth

Pregnancy And Childbirth

If Pregnancy Is Something That Frightens You, It's Time To Convert Your Fear Into Joy. Ready To Give Birth To A Child? Is The New Status Hitting Your State Of Mind? Are You Still Scared To Undergo All The Pain That Your Best Friend Underwent Just A Few Days Back? Not Convinced With The Answers Given By The Experts?

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