Info

Figure 3 Production of hydrogen (H2) and methane (CH4) in a patient with bacterial overgrowth of the small bowel (SBBO). Fasting H2 and CH4 production at-10 and 0 minutes; 10 grams of lactulose was administered at 0 minutes.

positive when the hydrogen concentration increases by 14-20 ppm (85). Smoking and exercise are not allowed during the test, and the day previous to the test (86). The hydrogen breath test shows stable intra-individual results in healthy people. However, in patients with high values there is a large day-to-day variation (87). The coefficient of variation is 5-10% (84,88). Sensitivity of 93% and specificity of 78% have been described (85). The glucose hydrogen breath test has a sensitivity of 62% and a specificity of 83% compared with jejunal culture (51). Poor sensitivity due to rapid absorption of glucose substrate in the proximal small bowel, which inhibits hydrogen generation, can be explained by a washout effect of concomitant diarrhea, loss of bacterial microbiota because of recent antibiotic therapy, or an acidic bowel lumen.

Was this article helpful?

0 0
Pregnancy And Childbirth

Pregnancy And Childbirth

If Pregnancy Is Something That Frightens You, It's Time To Convert Your Fear Into Joy. Ready To Give Birth To A Child? Is The New Status Hitting Your State Of Mind? Are You Still Scared To Undergo All The Pain That Your Best Friend Underwent Just A Few Days Back? Not Convinced With The Answers Given By The Experts?

Get My Free Ebook


Post a comment