These microorganisms possess various immunological functions viz., mitogenic activity (36), adjuvant activity (21), macrophage activation (37), enhancement of antibody production (38), induction of interferon-g production (39) and antitumor effects (40), amongst others. It has further been indicated by a number of studies that both the cell wall and cytoplasm of specific probiotic bacteria induced mitogenic responses of spleen cells (37,41,42).
Health benefits of probiotic organisms related that may impact on the gut microbiota are summarized in the following paragraphs.
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