Conclusion

The area of modulation of gastrointestinal microbiota through intake of probiotics seems to hold much promise for the prophylactic management and/or treatment of gut disorders, as mediated by pathogens. The growing realization by consumers that our food profoundly influences our health has fueled the introduction of food products with health claims such as probiotics into the market. It seems that the use of probiotics in general clinical practice is not far away, given that products such as VSL#3, containing a mixture of lactic acid bacteria probiotics, are already being used. However, it is relevant to note that studies on particular strains may not necessarily be extrapolated to all probiotic microorganisms. Molecular tools will continue to be used to understand and manipulate probiotic bacteria with a view to produce vaccines and new and improved products. The critical step in wider application will be to make products available that are safe and clinically proven in a specific formulation easily accessible to physicians and consumers. Systematically randomized, double-blind and placebo-controlled studies including large numbers of human volunteers are needed to advance the scientific knowledge of probiotics and gastrointestinal microbiota. Technological advances like protective coating(s), micro-encapsulation, or addition of prebiotic compounds that can serve as growth factors for probiotic organisms will improve the survival of strains in the gut of consumers. It is necessary to clearly understand the functionality of these organisms in the intestinal ecosystem.

Pregnancy And Childbirth

Pregnancy And Childbirth

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