Aminoglycosides

Tobramycin

Two dosing regimens of tobramycin have been compared for the selective decontamination effect of the digestive tract in healthy volunteers (85). Both regimens markedly suppressed the number of aerobic Gram-negative rods while the higher dose also had an effect on the anaerobic microbiota as evidenced by low concentrations of beta-aspartylglycine.

Nitrofurantoin

Nitrofurantoin has been used for prophylaxis in women with recurrent urinary tract infections (86). The effect on the fecal microbiota was examined semi-quantitatively. The agent had no effect on the numbers of enterococci or enterobacteria and no resistant strains or overgrowth of strains was detected.

Pregnancy And Childbirth

Pregnancy And Childbirth

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