by Christian Hoffmann and Gerd Fatkenheuer
The following describes several opportunistic infections that rarely occur in central Europe, or have become very rare as a result of HAART. These diseases include aspergillosis, bacillary angiomatosis, histoplasmosis, isosporiasis, coccidioidomy-cosis (Coccidioides immitis), visceral leishmaniasis, microsporidiosis, Penicillium marneffei mycosis and rhodococcosis. These infections affect HIV patients more frequently than immunocompetent individuals, have more serious courses of disease than in HIV-negative patients and recur more frequently. Despite this, only three, namely histoplasmosis, isosporiasis and coccidioidomycosis, are AIDS-defining according to the current CDC/WHO classification.
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