Prophylaxis of Arterial Thromboembolism

Danaparoid has been used to prevent arterial thromboembolism in patients undergoing various vascular operations, including peripheral artery bypass graft surgery, embolectomy, and endarterectomy. In these patients, it was given as a preoperative iv bolus of 2500 or 2250 U, and in some it was also administered postoperatively. Given as an iv bolus of 2500 or 2250 U immediately before the procedure, danaparoid has also been used to provide antithrombotic cover during percutaneous coronary intervention (PCI), with or without stenting, and for insertion of intra-aortic balloon devices.

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