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aPretest probability score: 6-8 = high; 4-5 = intermediate; 0-3 = low.

bFirst day of immunizing heparin exposure considered day zero; the day the platelet count begins to fall is considered the day of onset of thrombocytopenia (it generally takes 1-3 more days until an arbitrary threshold that defines thrombocytopenia is passed). In general, giving heparin during or soon after surgery is most likely to induce immunization. The scoring system shown here has undergone minor modifications from previously published scoring systems (Warkentin, 2003; Warkentin and Heddle, 2003).

Abbreviations: ASR, acute systemic reaction (Table 5); DVT, deep venous thrombosis; HIT, heparin-induced thrombocytopenia.

aPretest probability score: 6-8 = high; 4-5 = intermediate; 0-3 = low.

bFirst day of immunizing heparin exposure considered day zero; the day the platelet count begins to fall is considered the day of onset of thrombocytopenia (it generally takes 1-3 more days until an arbitrary threshold that defines thrombocytopenia is passed). In general, giving heparin during or soon after surgery is most likely to induce immunization. The scoring system shown here has undergone minor modifications from previously published scoring systems (Warkentin, 2003; Warkentin and Heddle, 2003).

Abbreviations: ASR, acute systemic reaction (Table 5); DVT, deep venous thrombosis; HIT, heparin-induced thrombocytopenia.

thrombocytopenia; such clinical scenarios have been reported (Warkentin, 2005). Another feature of this system is that very low platelet count values (i.e., 10-19 and <10 x 109/L) score only 1 and 0 points, respectively, thus reducing the chance that a patient with posttransfusion purpura (PTP) or DITP will be misclassified as HIT and inappropriately given anticoagulant therapy.

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