Index

Acenocoumarol anticoagulation, 394

Acetylsalicylic acid (ASA), 303, 466 Acquired anticoagulant deficiency, 22, 42-44, 210, 271, 302-305, 398-399

Acral (extremity) necrosis, 38-42 Activated partial thromboplastin time (aPTT), 12, 13, 101, 214, 267, 291-293, 295, 302, 327, 331, 343-354, 365-369, 381-382, 384-387, 389, 392, 397, 400, 412-418, 428, 445, 469, 470-472, 474, 475, 489, 510 coumarin influence on, 297 influence on efficacy and safety of lepirudin, 358, 361, 365 Acute coronary syndrome (ACS), 441

frequency of HIT in, 71, 86 bivalirudin treatment of, 422-424 fondaparinux treatment of,

447-448, 453 lepirudin treatment of, 353,

365-367 oral factor Xa and thrombin inhibitors for, 453-454 Acute systemic reaction (ASR), 22, 24, 26, 51, 53, 298 definition and clinical features of,

49-50 hemodialysis and, 464 Adenocarcinoma, 42, 261-265, 274-275 venous limb gangrene complicating, 263-265 Adenosine diphosphate (ADP), 7, 50, 119, 217, 218, 229, 230, 266, 269, 414, 415 potentiator of platelet activation by HIT antibodies, 138, 191-193, 234-235

Adjunctive therapies for HIT,

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