HITIgG detectable

HIT-IgG not detectable

^Unfractionated Heparin (UFH))

^Unfractionated Heparin (UFH))

Typical-onset HIT

Delayed-onset HIT

Rapid-onset HIT

can occur if heparin given and HIT-IgG still present (usually within 100 days)

? Low risk for recurrent HIT with future heparin use

Associated with coumarin (e.g., warfarin) treatment of DVT complicating HIT. b Upper limb, mesenteric and renal artery thrombosis can complicate HIT.

0 In some patients with rapid-onset HIT, thrombocytopenia may not have complicated the recent heparin exposure. DVT, Deep-vein thrombosis; Ml, Myocardial infarction; PE, Pulmonary embolism.

0 0

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