Heparin Reexposure of the Patient with Acute or Recent HIT

Recommendation. Deliberate reexposure to heparin of a patient with acute or recent HIT for diagnostic purposes is not recommended. Rather, the diagnosis should first be excluded or confirmed in most situations by testing acute patient serum or plasma for HIT antibodies using a sensitive activation or antigen assay (Grade 1C).

Heparin Reexposure of the Patient with a History of Remote HIT Recommendation. Heparin should not be used for antithrombotic prophylaxis or therapy in a patient with a previous history of HIT, except under special circumstances (e.g., cardiac or vascular surgery) (Grade 2C).

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