Cerebral Venous Dural Sinus Thrombosis

Thrombosis of the dural venous sinuses is an unusual cause of stroke in HIT patients that was first reported by Stevenson (1976). Often, there is a second hypercoagulable state, such as pregnancy (Van der Weyden et al., 1983; Calhoun and Hesser, 1987) or myeloproliferative disease (Kyritsis et al., 1990), that may have interacted with HIT to cause this complication. Platelet-rich "white clots" were identified in the superior sagittal venous sinus in one necropsy study (Meyer-Lindenberg et al., 1997). Clinicians should have a high index of suspicion for dural sinus thrombosis when a patient develops progressive focal neurological signs, decreased level of consciousness, seizures, or headache during or soon after stopping heparin treatment (Beland et al., 1997; Pohl et al., 1999, 2000; Warkentin and Bernstein, 2003). Treatment includes immediate discontinuation of heparin, use of an alternative anticoagulant, and possibly, intravenous gammaglobulin (see Chapter 12).

Headache Happiness

Headache Happiness

Headache Happiness! Stop Your Headache BEFORE IT STARTS. How To Get Rid Of Your Headache BEFORE It Starts! The pain can be AGONIZING Headaches can stop you from doing all the things you love. Seeing friends, playing with the kids... even trying to watch your favorite television shows. And just think of how unwelcome headaches are while you're trying to work.

Get My Free Ebook

Post a comment