Anticoagulation of the HIT Patient Without Thrombosis

Recommendation. Patients suspected to have acute HIT should undergo imaging studies for lower limb DVT, especially those at highest risk for venous throm-boembolism, such as postoperative patients (grade 1C).

Recommendation. Alternative therapeutic-dose anticoagulation with an appropriate anticoagulant, such as danaparoid, lepirudin, or argatroban, should be considered in patients strongly suspected (or confirmed) to have HIT even in the absence of symptomatic thrombosis. Anticoagulation should be continued at least until recovery of the platelet counts to a stable plateau (grade 1C).

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