Physical and Biological Bases of Spatial Distortions in Positron Emission Tomography Images

Magnus Dahlbom 1 Introduction 439

Sung-Cheng (Henry) Huang 2 Physical Distortions of PET 439

UCLA School of Medicine 2.1 Nonuniform Sampling • 2.2 Nonuniform Spatial Resolution Variations • 2.3 Axial Sampling •

2.4 Attenuation Correction

3 Anatomical Distortions 441

3.1 Elastic Deformations • 3.2 Different Image Distributions • 3.3 Motion • 3.4 Movement •

3.5 Intersubject Variability

4 Methods of Correction 444

4.1 Physical Factors • 4.2 Elastic Mapping to Account for Deformation and Intersubject Variability

5 Summary 446

References 446

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