There are many situations in 3D biomedical imaging in which identification, generation, and display of the optimal image plane is critical. The utility of 2D images often depends on the physical orientation of the image plane with respect to the structure of interest [2,16,51,54]. Most biomedical imaging systems have limited capability to create this optimal 2D image directly, as structure positioning and scanner orientation are generally restricted. Therefore, techniques to generate and display these optimal 2D images from 3D volume images are particularly important, allowing the orientation of the 2D image plane to ultimately result in a clear, unrestricted view of important features.
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