Concluding Remarks

There are numerous research challenges in the field of biomedical image segmentation. Some of these research opportunities are extensions, generalizations, and improvements over existing methods. For instance, a method that combines intensity and anatomic (shape) information for segmentation of brain images and accurate elastic registration of brain images into a prelabeled stereotaxic space would allow automated quantification of the regional and global volumetric structure of the brain. Other major challenges include the development of more general segmentation methods that do not depend on specific conditions such as imaging modality, protocols, image resolution, and specie being imaged. In addition, there is a substantial need to develop methods that

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