C

FIGURE 8 Some examples of CT-MRI registration. (A) MRI slice of a brain tumor patient with an inset of matched CT. The MRI clearly shows abnormal anatomy around the operation bed, while in the CT scan the brain around the operation bed (the dark spot) looks normal. In this case, the MRI is essential for accurate targeting of the tumor volume for radiotherapy. (B) Quality assurance of CT-MRI matching of the pelvis. The CT bone is overlaid in white over the MRI (bone is black in MRI). (C) Matching the same data without first erasing the femurs (Fig. 6a) leads to a grossly incorrect match (target registration error of about 1.5 cm).

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