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Biosynthesis of b-Amino Acids by Catabolic Pathways

1.6.2.1 b-Alanine

Precursors of ¿-alanine 3 biosynthesis are uracil 2, L-aspartate 4, and polyamines which are subjected to degradation in distinct ways - whereas uracil is metabolized by hydrogenation followed by hydrolysis, polyamines like spermine 1 are oxidized and L-aspartate is decarboxylated (Scheme 1.6.1).

Scheme 1.6.1. Biosynthetic pathways to ¿-alanine 3.
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