Another possible means of conversion of functionalized arenes into the corresponding hydrocarbons is the reduction of diazonium compounds [49]. By appli cation of this method cinnamic esters were synthesized in a sequence starting from the iodoarene resin 135. Heck coupling with acrylates, using palladium catalysis, affords an immobilized cinnamate. This can be detached after a sequence of transformations, yielding to an allyl amine in a traceless fashion (Scheme 6.1.34).


0 0

Post a comment