G

Lys-Trp-Lys

Lys-Trp-Lys

Lys-Tyr-Lys

Lys-Tyr-Lys

> Lys-Trpox-Lys

> Lys-Trpox-Lys

Fig. 4.6.5. Assay for spectroscopic investiga- reactivity. The radical of Lys-Trp-Lys forms tion of how aromatic amino acids modulate oxidized peptide products in the presence of

DNA-mediated HT. The peptide radicals gen- O2 whereas the radical Lys-Tyr-Lys forms cross-

erated by DNA-mediated HT have different links with the DNA bases at the binding site.

Lys-Tyr-Lys-DNA adducts

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