Hypertrophy and hyperplasia are two ways by which the cell mass of the body increases.

a. With HYPERTROPHY, there is an increase in the size of the individual cells. No new cells are formed. An example is the enlargement of muscles due to exercise by the increased diameter of the individual striated muscle fibers.

b. With HYPERPLASIA, there is an increase in the total number of cells. An example of abnormal hyperplasia is cancer.

c. ATROPHY is seen when there is a loss of cellular mass.

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