Many chronic suppurative lesions such as chronic osteomyelitis and chronic leg ulcers are well known for their potential for malignant transformation into squamous cell carcinoma [69, 70]. The resultant tumours are known as Marjolin's ulcers, named after Marjolin's first description in 1826 . Such tumours have been described in HS.
scribed in women [5, 53, 54, 74, 85, 88, 91, 92]. This may however partly be explained by reporting bias. For instance, vulval squamous cell carcinomas may well be under-reported in association with HS, as this diagnosis was explicitly excluded from Mora's series of squamous cell carcinoma in a black population. Predisposing factors are rarely searched for in the literature. The occurrence of non-skin cancers suggests that general carcinogens such as tobacco may play a role. Some authors have suggested that skin cancers predominate in the perineal region [52, 82], which raises the possibility of co-carcinogenic factors such as human papilloma virus (HPV) [52, 87, 88] and/or past radiotherapy [72, 88]. The presence of these factors and other known carcinogen exposure should reinforce vigilance and encourage physicians to perform a biopsy in any case of suspicious HS lesions.
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Complete Guide to Preventing Skin Cancer. We all know enough to fear the name, just as we do the words tumor and malignant. But apart from that, most of us know very little at all about cancer, especially skin cancer in itself. If I were to ask you to tell me about skin cancer right now, what would you say? Apart from the fact that its a cancer on the skin, that is.