Side Effects

Etretinate is a prodrug of acitretin with a molecular weight about 10% greater than that of acitretin, with the consequence that the daily dose, usually 30-75 mg etretinate, corresponds to 20-50 mg acitretin. In the early 1990s, many patients had been treated with either etretinate or isotretinoin for as many as 15 years and had not developed any signs of severe toxicity [39]. Acitretin has been established as a safe, effective treatment for psoriasis [39-41]. Retinoids, including etretinate and acitretin, are potent teratogens, leading to strict requirements for pregnancy prevention during and after their use [39-41]. Etretinate can be prescribed for male patients or postmenopausal female patients [41]. Premenopausal fertile woman should not be treated with etretinate but can be considered for acitretin therapy providing they use adequate contraception during therapy and for 24 months [39, 41] or even 36 months [40] after discontinuation. In fertile female patients it is also suggested to do a pre-treatment pregnancy test and repeated pregnancy tests every month of therapy [41].

Natural Treatments For Psoriasis

Natural Treatments For Psoriasis

Do You Suffer From the Itching and Scaling of Psoriasis? Or the Chronic Agony of Psoriatic Arthritis? If so you are not ALONE! A whopping three percent of the world’s populations suffer from either condition! An incredible 56 million working hours are lost every year by psoriasis sufferers according to the National Psoriasis Foundation.

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