References

1. Jemec GBE. Hidradenitis suppurativa. J Cut Med Surg. 2003; 7: 47-56.

2. Larko O. Photodynamic therapy. Aust J Dermatol Suppl. 2005; 46: S1-2.

3. Nyb^k H, Jemec GBE. Photodynamic therapy of acne rosacea. Dermatology 2005; 211: 135-138.

4. Charakida A, Seaton ED, Charakida M, Mouser P, Avgerinos A, Chu AC. Phototherapy in the treatment of acne vulgaris: what is its role? Am J Clin Dermatol. 2004; 5: 211-216.

5. Gold M, Bridges TM, Bradshaw VL, Boring M. ALA-PDT and blue light therapy for hidradenitis suppurativa. J Drugs Dermatol. 2004; 3 (1 Suppl): S32-35.

6. Strauss RM, Pollock B, Stables GI, Goulden V, Cun-liffe WJ. Photodynamic therapy using aminolaevu-linic acid does not lead to clinical improvement in hidradenitis suppurativa. Br J Dermatol. 2005; 152: 803-804.

7. Zeligman I. Temporary x-ray epilation therapy of chronic axillary hidradenitis suppurativa. Arch Dermatol. 1965; 92: 690-694.

8. Frohlich D, Baaske D, Glatzel M. [Radiotherapy of hidradenitis suppurativa - still valid today?] Strahlenther Onkol. 2000; 176(6): 286-289.

9. Jemec GBE, Hansen U. The histology of hidradenitis suppurativa. J Am Acad Derm 1996; 34: 994-999.

10. Morgan WP, Leicester G. The role of depilation and deodorants in hidradenitis suppurativa. Arch Der-matol. 1982; 118: 101-102.

11. Jemec GBE, Heidenheim M, Nielsen NH. Hidradenitis suppurativa: characteristics and consequences. Clin Exp Dermatol 1996; 21: 419-423.

12. Tack B. [Laser and intense pulsed light for hair removal.] Ann Dermatol Vener. 2005; 132: 75-79.

13. Bong JL, Shalders K, Saihan E. Treatment of persistent painful nodules of hidradenitis suppurativa with cryotherapy. Clin Exp Dermatol. 2003; 28: 241-244.

14. Lewis V, Finlay AY. 10 years experience of the Dermatology Life Quality Index (DLQI). J Investig Dermatol Symp Proc. 2004; 9: 169-180.

Table 24.2. Factors to consider when planning experimental studies of physical therapies. Controls are essential and should be set up for each lesion and for the patient. Inguinal lesions are not appropriate controls for axillary lesions. (DLQI Dermatology Life Quality Index, IPL intense pulsed light)

Element of study

Example

Classification and characterization of cases

Hurley classification

Randomization of patients and lesions

Flipping coins or drawing lots

Outcome variables defined

Should include subjective, e.g., DLQI, and objective, e.g., Sartorius score, elements

Standardization of therapy

Depilation using a IPL device at a specific setting for a set number of treatments

Follow-up

Minimum 3 months, and preferably longer

15. Finlay AY. Quality of life assessments in dermatol- 16. Sartorius K, Lapins J, Emtestam L, Jemec GB (2003) ogy. Semin Cutan Med Surg. 1998; 17: 291-296. Suggestions for uniform outcome variables when reporting treatment effects in hidradenitis suppurativa. Br J Dermatol 149:211-213.

Chapter 25

Treatment

25

Gregor B.E. Jemec, Jean Revuz

Contents

25.1 Introduction 183

25.2 Staging the Disease 183

25.3 Treatment of Hidradenitis Suppurativa Hurley Stage I 184

25.4 Treatment of Hidradenitis Suppurativa Hurley Stage II 184

25.5 Treatment of Hidradenitis Suppurativa Hurley Stage III 185

25.6 Hidradenitis Suppurativa with Cysts 185

25.7 Experimental Therapies 186

25.8 General Requirements for Treatment ... 186

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