The histological similarities and co-occurrence of HS and Crohn's disease have led to speculation that treatments used for Crohn's disease may have a role in the management of HS as well. This is further supported by the beneficial effects of biologics in HS (see Chap. 20). Methotrexate is another drug used in Crohn's disease that has been evaluated in a small open case series. The results were variable, and although individual patients experienced some relief from symptoms, an overall evaluation suggested only a weak effect on the severity of HS flares and no apparent effect on the recurrence rate [12]. It is possible that a higher dose of methotrexate than the one examined could influence the results positively.

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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