Key points

■ The pathogenesis of hidradenitis suppurativa (HS) is still poorly understood and not yet clearly defined

■ A large variety of bacteria can be found in HS lesions and many of them belong to the normal flora of the skin

■ In the studies using the bacteria prevalent on the surface of the lesions there is possible contamination from the resident flora of the skin

■ In cases of cultures obtained from the deeper parts of HS, Staphylococcus aureus, coagulase-negative staphylococci and anaerobic bacteria have commonly been isolated

■ The first event seems to be follicular occlusion by keratinized stratified squamous epithelium in apocrine-bearing areas, with subsequent inflammation

■ The initial inflammatory change can be produced by a pyogenic bacterial infection or by factors similar to those involved in acne

■ In chronic lesions, bacteria represent a risk factor for the destructive scarring and extension of the disease and secondary bacterial infections may

Antibiotics do not cure the disease but they may relieve the symptoms through either an antibacterial or an anti-inflammatory effect

Contents

11.1 Normal Microflora of the Skin 86

11.2 Bacteria Found in HS Lesions 87

11.3 General Factors About Bacterial Involvement in HS Pathogenicity 90

11.4 The Role of Antibiotics in the Treatment of HS 91

11.5 Possible Consequences for Bacterial Ecology due to Antibiotic Treatment in HS 92

References 92

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How To Reduce Acne Scarring

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