Isotretinoin in Combination Treatment of HS

One author reported on a patient with Crohn's disease and HS who showed a satisfactory outcome following treatment with azathioprine (150 mg/day) and methylprednisolone (16 mg/ day) combined with isotretinoin (0.7 mg/kg per day) and periodic administration of antibiotics [28]. Another report details a patient with multiple pustular and cystic lesions located on swollen and red labia majora. She was successfully treated with prednisolone and erythromycin for months and then long-term isotretinoin (mostly 1.0 mg/kg per day) for 15 months, and no significant relapse of the so-called vulval apocrine acne occurred during a follow-up period of 10 months [29].

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