A number of diseases have been described as co-occurring with HS. The association may often occur by chance taking into account the prevalence of HS in the general population. The serendipitous observation of co-occurrence may however also reflect a causal relationship between the diseases, and thereby lead to a better aetiological or pathogenic understanding of both diseases. Taking all the suggested associations into account a very heterogeneous picture emerges, which does not allow hard conclusions to be made. This review of the literature strongly underlines the continued need for systematic observations in larger numbers of patients. The establishment of patient cohorts of sufficient size to allow longitudinal studies is therefore encouraged.
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