Clinical Presentation

Symptoms depend on disease location (colonic lesions being more expressive) and anatomical severity. Patients usually present with diarrhea, mucous and blood discharges, abdominal pain, and weight loss. Other features of flares are fatigue, fever, articular, cutaneous and ocular manifestations, and biological inflammatory response (elevated C-reactive protein and eryth-rocyte sedimentation rate, ESR). In some cases, the disease is latent until the development of a complication, a stricture causing an intestinal obstruction or a perforation (peritonitis, or more commonly internal fistula with abscess formation). The course of CD is poorly predictable. Most patients have flares separated by remission phases of variable duration; others (about 10%-15%) have a chronic active disease. The disease has a protracted benign course in fewer than 15% of patients.

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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