Cathelicidins

LL-37 (CAP18), the only human antimicrobial peptide that has been identified in the cathelici-din gene family, is produced in neutrophils and also induced in keratinocytes during inflammatory skin disorders [17, 43]. In vivo, LL-37 provides protection against necrotic skin infection caused by group A streptococci and it also exerts antimicrobial activity against a wide variety of Gram-positive and Gram-negative bacteria [52]. Similar to defensins, LL-37 plays multiple roles in the fight against pathogens: in addition to its antibiotic effect, it has the potential to recruit mast cells, neutrophils, mono-

cytes, and T cells to inflammation foci, and it is involved in the re-epithelialization of skin wounds [14, 29, 56].

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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