Acknowledgements

We thank Dr. Anders Johannesson for his valuable comments about previous versions of the manuscript, Dr. Karin Sartorius for useful advice, Dr. Zoe and Francis P. Walsh for linguistic revision and Gun-Britt Karlberg and Barbro Andersen for their help. This work was supported by grants from Karolinska Institutet, the Edvard Welander Foundation, Finsen Foundation and the Foundation for Cancer and Allergy Research.

22.6.3.4 Concluding Remarks

No exact estimates of the costs have been made but, but there are at least three reasons why carbon dioxide laser is less expensive than traditional excisional surgery. Firstly, the total operation time is shorter, which keeps the need for qualified personnel to a minimum, and permits a more rational use of room facilities. Secondly, there is no need for nursing assistance postop-eratively. Thirdly, the postoperative symptoms are less and fewer patients have to refrain from work. A more detailed cost-benefit analysis of this method remains to be done. The patients we selected were at Hurley Stage II, which we predefined as operable by our method. Patients classified as Hurley Stage III were referred for

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