And the Pilosebaceous Unit

Pilosebaceous Unit

The sebaceous glands are an integral part of the pilosebaceous unit and are found over the entire body surface with the exception of the palms and soles. The gland itself is made up of several lobules, which are separated by vascular connective tissue. These lobules all empty into a short duct which then empties into the upper part of a hair follicle at the level of the infun-dibulum. More than one sebaceous duct may drain into the upper part of the hair follicle. Fig. 4.2. Diagrammatic...

Established Hidradenitis Suppurativa Fig 44ae

Inflammation Apocrine Glands

Biopsy samples from established HS lesions show sinus tracts with marked suppuration and frank abscess formation. The sinuses are lined by stratified epithelium and are surrounded by fibrosis and inflammation. The squamous epithelium extends from the associated follicular epithelium. The inflamed sinus tracts frequently contain desquamated keratin and hair shafts within the dense fibrosis 6 . Within the adjacent connective tissue there is frequently a dense chronic inflammatory infiltrate,...

Follicular Occlusion Diseases

Follicular occlusion diseases or perifolliculitis capitis abscedens et suffodiens The term follicular occlusion disease refers to a possible common pathogenic mechanism of occlusion of sebaceous or apocrine glands, and diseases included in this term are listed in Table 6.1. An association of these disorders has been described in several patients, suggesting that a causal relationship may be found rather than mere co-occurrence. It has therefore been suggested that the association of...

Hidradenitis Surgery Before And After

Hidradenitis Suppurativa Pictures

Hidradenitis suppurativa HS, synonym acne inversa is a cicatrizing and frequently persistent inflammatory disorder of the sebaceous follicles and terminal hair follicles of apocrine-gland-bearing areas in the adult 12, 31 . The condition may remain relatively mild but nevertheless distressing 32 , ranging from a few but recalcitrant suppurating lesions to an advanced widespread and disabling disease lasting for years or decades. Possible consequences of longstanding, recurrent disease are...