Summary

Cellular physiological functions are regulated via signaling mechanisms in essentially any cell type of any organ. Although myocardial cells are unique in that they are interconnected to each other with gap junctions and act as an electrical syncytium, there is nevertheless an enormous number of important cellular receptors that allow the cells to receive and respond to various signals. This chapter reviewed the role and signaling mechanisms of selected physiologically and pathophysiologically important cardiac and vascular receptors, with emphasis not only on G protein-coupled receptors (e.g., p-ARs), but also on non-G protein-coupled receptor systems, such as GC-related receptors (e.g., receptors for nitric oxide).

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